Home > Salary > South Africa > Medical Affairs Manager
A Medical Affairs Manager is responsible for overseeing the medical and scientific activities within a pharmaceutical or healthcare organization. They play a crucial role in bridging the gap between the medical and commercial aspects of the company. Their primary responsibilities include developing and implementing medical strategies, providing medical expertise to support product development and marketing, managing relationships with key opinion leaders and healthcare professionals, and ensuring compliance with regulatory guidelines.
This role requires strong leadership and communication skills, as well as a deep understanding of medical and scientific concepts. Medical Affairs Managers must stay updated with the latest research and industry trends, and be able to effectively communicate complex medical information to both internal and external stakeholders. They work closely with cross-functional teams, including research and development, marketing, regulatory affairs, and sales teams.
Estimated Yearly Salary: 320,984 ZAR
Estimated Monthly Salary: 26,749 ZAR
Estimated Weekly Salary: 6,173 ZAR per week
Estimated Hourly Salary: 154 ZAR per hour
Values are pre-tax
Last revision of data: 2025-01-04
Estimated Monthly Salary: 25,865 ZAR
Estimated Weekly Salary: 5,969 ZAR per week
Estimated Hourly Salary: 149 ZAR per hour
Last revision of data: 2024-01-05
Estimated Yearly Salary: 16,013 USD
Estimated Monthly Salary: 1,334 USD
Estimated Weekly Salary: 308 USD per week
Estimated Hourly Salary: 8 USD per hour
Difference in salary year over year or average salary increase is approximately
3 %
Data confidence is - relatively high
Data fetched from dabase: 14 submissions.
Results are anonymized. Amounts indicated are pre-tax, meaning no deductionts yet have been made to the basic salary. Salaries where there are less than 3 entries are not displayed.
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Estimated Yearly Salary: 320,984 ZAR
Estimated Monthly Salary: 26,749 ZAR
Estimated Weekly Salary: 6,173 ZAR per week
Estimated Hourly Salary: 154 ZAR per hour
By working as Medical Affairs Manager a person can save up to 1,063 USD per month or 12,759 USD yearly. Values are pre-tax.
NOTE: These values are estimates and are averaged for the whole country. Furthermore the value is likely exaggerated as no other expenses are taken into account in the projection. Unessential expenses are very subjective and are difficult to assess. Most likely the previously estimated number is significantly lower for majority of people. Expenses in different cities across the country may vary. Above values accuracy is low and is based on limited set of data obtained.
For more information regarding expenses in South Africa, see costs of living in South Africa.
Estimated Yearly Salary for Medical Affairs Manager
Last revision of data: 2025-01-04
Data as of 2025
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Medical Affairs Manager salary in South Africa
Average Yearly Salary of Medical Affairs Manager in South Africa is approximately 320,984 ZAR (16,013 USD). Data is for 2025 and indicates a pre-tax value. The salary itself depends on multiple factors such as seniority, job performance, certifications, experience or any other bonuses. The value indicated is an average amount based on records we have in database. Real values may vary. The data is for orientational purposes.
What does Medical Affairs Manager do?

Skills: Medical Affairs, Pharmaceutical, Healthcare, Medical Strategy, Key Opinion Leaders, Regulatory Compliance
Job industry: Pharmaceutical
Job industry: Pharmaceutical
How much does Medical Affairs Manager make?
Salary details
How much does Medical Affairs Manager make?Estimated Yearly Salary: 320,984 ZAR
Estimated Monthly Salary: 26,749 ZAR
Estimated Weekly Salary: 6,173 ZAR per week
Estimated Hourly Salary: 154 ZAR per hour
Comparing salary to last year:
Estimated Yearly Salary: 310,380 ZAREstimated Monthly Salary: 25,865 ZAR
Estimated Weekly Salary: 5,969 ZAR per week
Estimated Hourly Salary: 149 ZAR per hour
Medical Affairs Manager estimated salary in USD
For easier comparison here is an estimated salary in USD:Estimated Yearly Salary: 16,013 USD
Estimated Monthly Salary: 1,334 USD
Estimated Weekly Salary: 308 USD per week
Estimated Hourly Salary: 8 USD per hour
Difference in salary year over year or average salary increase is approximately
About these results
Data confidence is - relatively high Data fetched from dabase: 14 submissions.
Results are anonymized. Amounts indicated are pre-tax, meaning no deductionts yet have been made to the basic salary. Salaries where there are less than 3 entries are not displayed.
Want to check how your salary compares? Submit your own salary here
Compare salary to other countries
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Country:
Salary comparison to National average
South Africa is a diverse and vibrant country located at the southernmost tip of the African continent. It has a population of approximately 59 million people and covers an area of around 1.2 million square kilometers. The country is known for its rich cultural heritage, stunning landscapes, and abundant wildlife.
Estimated national average yearly salary is 126,956 ZAR (6,780 USD). Value indicated is pre-tax. Below graph shows estimated Medical Affairs Manager job salary compared to average salary in South Africa.
Comparison shows that a person working as Medical Affairs Manager in South Africa earns on average:
2.53 times the average salary (or 253% of average salary).
Estimated national average yearly salary is 126,956 ZAR (6,780 USD). Value indicated is pre-tax. Below graph shows estimated Medical Affairs Manager job salary compared to average salary in South Africa.
Comparison shows that a person working as Medical Affairs Manager in South Africa earns on average:
2.53 times the average salary (or 253% of average salary).
Is Medical Affairs Manager a well paid job?
Yes, our data show that Medical Affairs Manager is a very well paid job. With years and experience the salary might increase even further, resulting in higher satisfaction.What is considered a high salary for Medical Affairs Manager?
High salary for Medical Affairs Manager would be somewhere between 353,082 ZAR and 465,427 ZAR. However this is an estimation based on Gaussian Distribution.How much can you save working as Medical Affairs Manager in South Africa?
Living in South Africa the approximate monthly expenses are: 271 USD. This amount covers basic needs such as food, housing, clothing, healthcare and education costs for a single person. No luxury expenses such as traveling, leisure, hobbies are included in the estimation.Estimated Yearly Salary: 320,984 ZAR
Estimated Monthly Salary: 26,749 ZAR
Estimated Weekly Salary: 6,173 ZAR per week
Estimated Hourly Salary: 154 ZAR per hour
By working as Medical Affairs Manager a person can save up to 1,063 USD per month or 12,759 USD yearly. Values are pre-tax.
NOTE: These values are estimates and are averaged for the whole country. Furthermore the value is likely exaggerated as no other expenses are taken into account in the projection. Unessential expenses are very subjective and are difficult to assess. Most likely the previously estimated number is significantly lower for majority of people. Expenses in different cities across the country may vary. Above values accuracy is low and is based on limited set of data obtained.
For more information regarding expenses in South Africa, see costs of living in South Africa.
Salary comparison to region and neighbouring coutries
Country's neighbours are: Namibia, Botswana, Zimbabwe, Mozambique, Eswatini, Lesotho. To make it easier for comparison a conversion from local currency to USD has been made (conversion rates may vary).Estimated Yearly Salary for Medical Affairs Manager
Salary increase per years of experience
Based on data available the salary increase per years of experience is as following- 0 years (beginner) equals base salary
- 1 to 5 years of experience yields
- 6 to 10 years of experience yields
- 11 to 15 years of experience yields
- 16 to 25 years of experience yields
- more than 25 years of experience yields
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9. Oncologist
(1,071,922 ZAR per year, pre-tax.)
10. Urologist
(1,071,632 ZAR per year, pre-tax.)
Random salary:
Anesthesia technician (101,050 ZAR per year, pre-tax.)
Foodnutritional services director (107,694 ZAR per year, pre-tax.)
Assistant finance manager (123,396 ZAR per year, pre-tax.)
Commercial banker (236,667 ZAR per year, pre-tax.)
Virologist (211,360 ZAR per year, pre-tax.)
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